Endocrine Abstracts

Anaplastic thyropid carcinoma (ATC) is one of the most aggressive endocrine tumors with morphological features of undifferentiated neoplasm. Patients with ATC have a poor prognosis with a mean survival time of 2–6 months. Surgery, radiotherapy and chemotherapy do not improve survival rate. Bisphosphonates, analogs of endogenous pyrophosphates in which a carbon atom replaces the central oxygen atom, are successful agents for the prevention and treatment of postmenopausal o...